The National Academies of Sciences, Engineering, and Medicine will develop a Synthetic Biology Roundtable, in a neutral setting, for exploring synthetic biology and the associated science, policy and industry capabilities. The principal objective of the Roundtable is to improve coordination among the U.S. Army’s research and development stakeholders and to increase awareness in the broader open science community of current and future capabilities. The Roundtable will meet for three 1-day topical sessions. The first meeting will discuss the range of potential policy initiatives for the Army, the second meeting will discuss what synthetic biology sciences the Army might consider for its’ future battlefield, and the third will discuss what current industry and community capabilities the Army could leverage for partnerships. Meetings will be designed to facilitate a candid dialogue among participants and to foster effective collaboration between synthetic biology and Army communities. All activities of the Roundtable will be conducted in accordance with institutional guidelines.