The Science and Applications of Synthetic and Systems Biology: Workshop Summary (2011)
Chapter: Appendix B: Agenda
The Science and Applications of Synthetic and Systems Biology
March 14-15, 2011
Keck Building, Room 100
500 Fifth Street, NW
Washington, DC
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DAY 1: MONDAY, MARCH 14, 2011 |
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8:00–8:30 am |
Registration and Continental Breakfast |
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8:30–8:45 am |
Welcoming Remarks David Relman, M.D., Chair, and Jim Hughes, M.D., and Lonnie King, D.V.M., Vice-Chairs, Forum on Microbial Threats |
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8:45–9:30 am |
Keynote Remarks David Relman, Moderator Synthetic Biology and Biodefense Andrew Ellington, Ph.D., University of Texas at Austin |
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9:30–10:00 am |
Discussion |
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10:00–10:15 am |
Break |
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SESSION 1: The Promise of Synthetic and Systems Biology for the Understanding and Management of Infectious Diseases |
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10:15–10:45 am |
Synthetic biology, systems biology, and microbial threats James J. Collins, Ph.D., Boston University |
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10:45–11:15 am |
A metabolic engineering platform for discovery and production of new therapeutics Greg Stephanopoulos, Ph.D., Massachusetts Institute of Technology (MIT) |
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11:15–11:45 am |
Insights into pathogen-host interactions from systems biology Bernhard Palsson, Ph.D., University of California, San Diego |
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11:45–12:15 pm |
Commercial applications of synthetic biology David Berry, M.D., Ph.D., Flagship Ventures |
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12:15–12:45 pm |
Discussion |
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12:45–1:30 pm |
Lunch |
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SESSION 2: “The Basics” of Synthetic Biology: Bottom-Up vs. Top-Down Approaches |
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1:30–2:00 pm |
Systems for synthetic biology Hans Westerhoff, Ph.D., University of Manchester and the VU University Amsterdam |
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2:00–2:30 pm |
Design and complexity Herbert Sauro, Ph.D., University of Washington |
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2:30–3:00 pm |
DNA synthesis George Church, Ph.D., Harvard University |
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3:00–3:30 pm |
Synthetic biology “from scratch” Gerald Joyce, M.D., Ph.D., The Scripps Research Institute |
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3:30–3:45 pm |
Break |
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3:45–4:15pm |
Protein engineering and high throughput immune function analyses for the discovery of the next generation of protein therapeutics George Georgiou, Ph.D., University of Texas at Austin |
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4: 15–4:45 pm |
Synthesis and installation of genomes Clyde Hutchison III, Ph.D., J. Craig Venter Institute |
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4:45–5:15 pm |
Access through refactoring: Rebuilding complex functions from the ground up Chris Voigt, Ph.D., University of California, San Francisco |
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5:15–6:00 pm |
Discussion |
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6:00 pm |
Meeting Adjourns |
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DAY 2: TUESDAY, MARCH 15, 2011 |
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8:45–9:15 am |
Continental breakfast |
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9:15–9:30 am |
Summary of Day One and Preview of Day Two: David Relman, M.D., Chair, Forum on Microbial Threats |
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SESSION 3: Using Synthetic/Systems Biology Approaches to Manage Biofilms |
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9:30–10:00 am |
Harnessing and controlling social activities of bacteria E. Peter Greenberg, Ph.D., University of Washington |
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10:00–10:30 am |
Developing a synthetic biology device that detects biofilm formation on indwelling catheters Paul Freemont, Prof., Imperial College London |
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10:30–10:45 am |
Break |
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10:45–11:15am |
Novel approaches to combat biofilm drug tolerance Kim Lewis, Ph.D., Northeastern University |
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11:15–11:45 am |
Engineering viruses to destroy biofilms Timothy Lu, M.D., Ph.D., Massachusetts Institute of Technology |
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11:45–12:15 pm |
Discussion |
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12:15–1:00 pm |
Lunch |
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SESSION 4: Synthetic/Systems Biology Products and Platforms: Potential for Novel Preventives, Diagnostics, and Therapeutics in Infectious Diseases |
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1:00–1:30 pm |
Engineering microbial metabolism for production of antimalarial drugs Jay Keasling, Ph.D., University of California, Berkeley |
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1:30–2:00 pm |
Dynamics of clonal evolution: Immune system on a chip Jim Heath, Ph.D., California Institute of Technology |
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2:00–2:30 pm |
Using systems biology to understand and develop more effective vaccines Bali Pulendran, Ph.D., Emory University |
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2:30–2:45 pm |
Break |
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2:45–3:15 pm |
HTP screening system based on synthetic genes and proteins Stephen Johnston, Ph.D., Arizona State University |
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3:15–3:45 pm |
Synthetic biology and the art of biosensor design Chris French, Ph.D., University of Edinburgh |
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3:45–4:45 pm |
Open Discussion with Panelists, Forum Members, and Audience |
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4:45–5:00 pm |
Wrap-up Discussion, Jim Hughes and David Relman |
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5:00 pm |
Meeting Adjourns |
