Completed
The Forum on Neuroscience and Nervous System Disorders hosted a public workshop on March 20-21, 2017 that brought together key stakeholders from government, academia, industry, and disease-focused organizations to explore and advance efforts to identify biomarkers of neuroinflammation that can be validated and used in clinical development and regulatory decision making.
Featured publication
Workshop
·2018
Neuroinflammation is a burgeoning area of interest in academia and biopharma, with a broadly acknowledged role in many central nervous system (CNS) disorders. However, there is little agreement on the pathophysiological mechanisms that underlie the manifestations of neuroinflammation in the CNS comp...
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Description
An ad hoc committee will plan and conduct a 1.5-day public workshop that will bring together key stakeholders from government, academia, industry, and disease-focused organizations to explore and advance efforts to identify biomarkers of neuroinflammation that can be validated and used in clinical development and regulatory decision making.
Invited presentations and discussions will be designed to:
- Provide an overview of current knowledge on the role of neuroinflammation in non-infectious nervous system disorders -- including psychiatric and neurologic disorders, neurodevelopmental disorders, and neurodegeneration resulting from traumatic brain injury -- and discuss the various definitions of neuroinflammation in use across the field.
- Explore the state-of-the-science of neuroinflammation biomarkers and research needed to enable the use of these biomarkers at the individual level.
- Facilitate coordination among consortia and companies that are developing biomarkers of neuroinflammation.
- Highlight approaches, tools, and lessons learned that may apply across disorders and opportunities to advance the development of these biomarkers.
The committee will develop the agenda for the workshop, select and invite speakers and discussants, and moderate the discussions. A proceedings of the presentations and discussions at the workshop will be prepared by a designated rapporteur in accordance with institutional guidelines.
Contributors
Committee
Rita J. Balice-Gordon
Co-Chair
Linda Brady
Co-Chair
Brian Campbell
Member
Rosa Canet-Aviles
Member
Timothy Coetzee
Member
Richard J. Hodes
Member
Stuart W. Hoffman
Member
Eliezer Masliah
Member
Patricio O'Donnell
Member
William Z. Potter
Member
Richard Ransohoff
Member
Beth Stevens
Member
Stevin H. Zorn
Member
Sponsors
Department of Health and Human Services
National Science Foundation
Other, Federal
Private: For Profit
Private: Non Profit
Staff
Sheena Posey Norris
Lead
Clare Stroud
Lead
Daniel Flynn
Major units and sub-units
Health and Medicine Division
Lead
Board on Health Sciences Policy
Lead
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