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Biomarkers of Neuroinflammation: A Workshop

Completed

The Forum on Neuroscience and Nervous System Disorders hosted a public workshop on March 20-21, 2017 that brought together key stakeholders from government, academia, industry, and disease-focused organizations to explore and advance efforts to identify biomarkers of neuroinflammation that can be validated and used in clinical development and regulatory decision making.

Description

An ad hoc committee will plan and conduct a 1.5-day public workshop that will bring together key stakeholders from government, academia, industry, and disease-focused organizations to explore and advance efforts to identify biomarkers of neuroinflammation that can be validated and used in clinical development and regulatory decision making.
Invited presentations and discussions will be designed to:

  • Provide an overview of current knowledge on the role of neuroinflammation in non-infectious nervous system disorders -- including psychiatric and neurologic disorders, neurodevelopmental disorders, and neurodegeneration resulting from traumatic brain injury -- and discuss the various definitions of neuroinflammation in use across the field.
  • Explore the state-of-the-science of neuroinflammation biomarkers and research needed to enable the use of these biomarkers at the individual level.
  • Facilitate coordination among consortia and companies that are developing biomarkers of neuroinflammation.
  • Highlight approaches, tools, and lessons learned that may apply across disorders and opportunities to advance the development of these biomarkers.

The committee will develop the agenda for the workshop, select and invite speakers and discussants, and moderate the discussions. A proceedings of the presentations and discussions at the workshop will be prepared by a designated rapporteur in accordance with institutional guidelines.

Contributors

Committee

Rita J. Balice-Gordon

Co-Chair

Linda Brady

Co-Chair

Brian Campbell

Member

Rosa Canet-Aviles

Member

Timothy Coetzee

Member

Richard J. Hodes

Member

Stuart W. Hoffman

Member

Eliezer Masliah

Member

Patricio O'Donnell

Member

William Z. Potter

Member

Richard Ransohoff

Member

Beth Stevens

Member

Stevin H. Zorn

Member

Sponsors

Department of Health and Human Services

National Science Foundation

Other, Federal

Private: For Profit

Private: Non Profit

Staff

Sheena Posey Norris

Lead

Clare Stroud

Lead

Daniel Flynn

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